Analysis of ferritin levels in hemodialysis patients at Coronel Oviedo Regional Hospital, from April 2023 to March 2025
Article Sidebar
Main Article Content
Abstract
The study sought to analyze ferritin levels, a key indicator in the treatment of anemia and iron regulation in patients with (CKD) undergoing hemodialysis, which is a public health problem of great impact for both the state and the patient. The objective was to determine ferritin levels in patients aged 26 to 84 in the hemodialysis unit of Coronel Oviedo Regional Hospital during the period from April 2023 to March 2025. An observational, quantitative, and cross-sectional design was used, with 30 dialysis patients at Coronel Oviedo Regional Hospital. A male predominance of (86.7%) over female (13.3%) was identified, consistent with previous studies showing a higher prevalence of CKD in men. The most representative age group was 53 to 61 (33%), followed by 44 to 52 (23%) and 71 to 79 (20%). The majority of patients (93%) reside in Coronel Oviedo and (7%) in Carayaó. The analysis of pathologies showed that 53% (16) of the patients suffer from CKD as the main diagnosis. Ferritin levels were detected where 33% of patients had adequate levels (200-500 ng/ml). On the other hand, 17% maintained elevated levels (>800 ng/ml), which can represent a risk of iron overload, associated with chronic inflammation and systemic adverse effects.
Downloads
Article Details
This work is licensed under a Creative Commons Attribution 4.0 International License.
References
Organización Mundial de la Salud. Informe: “reduciendo riesgos y promoviendo un estilo de vida saludable”. 2002.
Erramouspe B. Determinación de Ferritina Sérica. Vol. 16. 2012.
World Health Organization. Data Global status report on noncommunicable diseases.
Hernández Sampieri R, Fernández Collado, C, Baptista Lucio, P. Metodología de la investigación. México: Mc Graw Hill; 2014.
Lepkowski JM, Tucker , Brick , de Leeuw ED, Japec , Lavrakas PJ, et al. Redalyc. [Online]; 2009. Disponible en: https://www.redalyc.org/pdf/997/99717150008.pdf.
Ministerio de Salud. Ministerio de Salud. [Online]; 2022. Disponible en: https://www.mspbs.gov.py/portal/26471/cada-vez-son-mas-los-pacientes-hemodializados-que-mejoran-su-calidad-de-vida.html.
Olmedo Mercado E, Giménez Vázquez FdJ, Rondelli Martínez LF, Ibáñez Franco EJ, Duarte Arévalos LE, Figueredo Martínez J, et al. UNI. [Online]; 2022. Disponible en: https://www.revistaspmi.org.py/index.php/rvspmi/article/view/294/226.
Leguizamón Picco G, Laura Elizabeth A, Martínez Evers I, Rodríguez Ríos E, Ramírez Piñánez, Rodríguez Avalos MS, et al. Universidad Católica. [Online]; 2024. Disponible en: file:///C:/Users/Admin/Downloads/520-Texto%20del%20art%C3%ADculo-1415-1-10-20240920%20(1).pdf.
Sánchez Cabezas AM, Morillo Gallego N, Merino Martínez RM, Crespo Montero. Scielo. [Online]; 2019. Disponible en: https://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S2254-28842019000300003.
Ferreira Ramírez E, Villalba González J, Chun Gauto A, Villanueva Sánchez, J, Martínez RN, Zayas Coronel, MdJ, et al. Universidad Nacional de Concepción. [Online]; 2023. Disponible en: https://revistas.unc.edu.py/index.php/fmunc/article/view/171/103.
Elio Giovanni P, Acevedo Ugarriza , Karina Inés E, Rodríguez Rios E, Ramírez Piñánez MA, Rodríguez Avalos , et al. Universidad Católica Nuestra Señora de la Asunción. [Online]; 2024. Disponible en: https://www.revistaspmi.org.py/index.php/rvspmi/article/view/520/334.
Vázquez Roa SL, Sosa de Sforza L, Vázquez Roa A. Insuficiencia renal crónica por fórmula MDRD-4: Prevalencia y factores de riesgo asociados en Villarrica, Paraguay. Mem. Inst. Investig. Cienc. Salud [Internet]. 2023 [citado 13 Oct 2023];21(1): e21122301. Disponible en: http://scielo.iics.una.py/scielo.php?script=sci_arttext&pid=S1812-95282023000100001. doi: https://doi.org/10.18004/mem.iics/1812-9528/2023.e21122301
Seifert A, Von Herrath D, Schaefer K: Iron overload, but not treatment with desferrioxamine favours the development of septicemia in patients on maintenance hemodialysis. Q J Med 65: 1015-1024, 1987.
Boelaert JR, Daneels RF, Schurgers ML, Matthys EG, Gordts BZ, Van Landuyt: HL: Iron overload in haemodialysis patients increases the risk of bacteriemia: A prospective study. Neph rol Dial Transplant 5: 130-134, 1990.
Eschbach JW, Adamson JW: Iron overload in renal failure patients: Changes since the introduction of erythropoietin therapy. Kidney Int 55 (Supt. .69): S 35-S 43, 1999.
Kalantar Zadeh K, Luft FC, Humphreys MB: Moderately high serum ferritin concentration is not a sign of iron overload in dialysis patients. Kidney Int. 56: 758-759, 1999.
Mahneusmith RL, Mahneusmith NIP: Bacteremic events are not associated with iron dextran administration or high serum ferritin in hemodialysis patients (abstract). J Am Soc Nephrol 10: 292, 1999.